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However, recent studies have suggested that its low bioavailability in the brain following oral administration, limits its usage and in long term, leads to liver damage (Qiu et al., 2016)

10.1021/tx300334w Chem

We cant draw any conclusions from cell-based studies

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J Am Coll Cardiol 57(16):16411649 Schultheiss HP, Fairweather D, Caforio ALP, Escher F, Hershberger RE, Lipshultz SE, Liu PP, Matsumori A, Mazzanti A, McMurray J, Priori SG (2019) Dilated cardiomyopathy