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In the nucleus, AR binds to the AR repressive protein Fox 01

Researchers who rush the escalation tend to experience more severe nausea, which can lead to skipped doses, inconsistent protocols, and ultimately worse outcomes

10.1038/s41385-022-00577-w

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Experiments showed that knocking down FTO in adult hippocampal neurons induced depression-like behavior, while overexpressing FTO reversed such behavior in response to unpredictable chronic mild stress