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15 A study of 54 patients diagnosed with SD compared with 54 healthy controls, assessed oxidative stress status and measured serum total antioxidant status (TAS), total oxidative status (TOS) and oxidative stress index (OSI)

Others choose monthly maintenance visits for general wellness or aesthetic goals

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There are two hit theories, the first hit for mitochondrial GSH depletion and ROS production and the second hit for JNK activation and translocation into mitochondria, aggravating ROS generation and mitochondrial membrane permeability transition (MPT), leading to hepatocyte death [5]