interaction of chloroacetamide electrophiles with cellular glutathion Selective covalent targeting GPX4 using masked nitrile-oxide Discovery of novel benzylaniline derivatives

Discovery of novel benzylaniline derivatives containing chloroacetamide as GPX4 inhibitors with potential efficacy in triple negative breast cancer ScienceDirect Advances in covalent drug discovery Nature Reviews Drug Discovery Design, synthesis, and biological evaluation of nitroisoxazole containing spiro[pyrrolidin oxindole] derivatives as novel glutathione peroxidase 4 mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation ScienceDirect Glutathione (GSH) is synthesized in the cytoplasm by the action of Download Scientific Diagram Structural and mechanistic analysis of covalent ligands targeting the RNA binding protein NONO: Cell Chemical Biology

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