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Monotherapy Results of studies with either single-agent isatuximab after daratumumab or daratumumab after isatuximab have provided evidence of limited efficacy for anti-CD38 antibody monotherapy in RRMM

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The compound supports angiogenesis, collagen synthesis, fibroblast activity, and nitric oxide pathway modulation, contributing to accelerated tissue recovery according to research published in the International Journal of Molecular Sciences

Pharmacokinetic characterization in porcine models demonstrated an intravenous half-life of approximately 3 minutes, with rapid degradation via sequential amino-terminal amino acid removal and confirmed oral bioavailability

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