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Common dose 200-300 mcg subQ nightly

Sleep Architecture and Delta-Wave Promotion: In rabbit, rat, cat, and limited human EEG studies, intravenous or intracerebroventricular DSIP administration significantly increased total sleep time, prolonged slow-wave sleep (SWS) duration, increased delta-wave power, and reduced sleep latency without altering REM sleep proportion

If your body changed soon after a new supplement entered the picture, its reasonable to treat that as a clue, not a coincidence to ignore

Vitiligo in a patient receiving infliximab for refractory ulcerative colitis