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As anticipated, MS analysis showed co-fractionation of Flag-Strep ASXL1 with other subunits of the PR-DUB BAP1 complex, including BAP1, HCF-1 and FOXK1/2, as well as MLL3 from MLL3/4 complexes (Fig

In the SAM, a similar redox-based antagonism is observed

Les taux de GSH ont augment de 40 % dans le sang total et de 100 % dans les cellules mononucles du sang priphrique en deux semaines

Valosin-containing protein (p97) is a regulator of endoplasmic reticulum stress and of the degradation of N-end rule and ubiquitin-fusion degradation pathway substrates in mammalian cells

In vivo imaging was performed at 2 h and 24 h post-injection via an IVIS imaging system