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10.3389/fendo.2021.621845 76 LiuJ.ZhaoY.ChenL.LiR.NingY.ZhuX

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In severe B12 deficiency, methylfolate is trapped in one form and can't be converted to the other folate forms cells need for DNA synthesis and cell division

Deficiencies in mitochondrial respiration and ATP production are likely responsible for hampering cell proliferative capacity, and may also be implicated in the repression of cell invasion, as migration and invasion throughout parenchyma is an energy-expensive process, particularly when moving through dense extracellular matrices [49]

It possesses sebum-regulating properties, helps improve skin barrier function, promotes skin hydration, and aids in the reduction of acne-related concerns