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Dysfunction of key astrocytic molecular systems, such as those mediated by the EAAT2, AQP4, and purinergic receptors, contributes to neurodegenerative and neurological diseases, including AD, ALS, epilepsy, MS, and sleep fragmentationassociated pathology

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doi: 10.1152/ajpgi.00302.2003

Tanaka T, Urata Y, Harada M, Kunitomi C, Kusamoto A, Koike H, Xu ZX, Sakaguchi N, Tsuchida C, Komura A, et al