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The mammalian target of rapamycin (mTOR) signaling pathway is a sensor of cellular stress and growth factor signals that regulates cell growth 35 and inhibit autophagy 36,37

The FSP 1 -CoQ 10 -NADPH pathway is an independent parallel system, also known as the non-dependent GSH/GPX 4 ferroptosis inhibition pathway, which is the main pathway of endogenous antioxidant enzyme regeneration, and synergistically inhibits lipid peroxidation and ferroptosis with GPX 4 and GSH ( 4 ) is an endogenous antioxidant that protects cells from ferroptosis by reducing lipid peroxidation