aldehyde glutathione Acetaldehyde-modified-cystine as an enhanced fluorescent probe for intracellular imaging Highly selective fluorescent recognition of

(2015), BioMed Research International 2015:648108, PubMed 26236730 Statistics from research literature Discovered by Loren Pickart in human blood plasma in 1973 , as a factor extending the longevity of cultured liver cells The smallest peptide with documented pharmacological activity: 3 amino acids (Gly-His-Lys) + one Cu ion Molecular weight: 402 Da EU cosmetic INCI name: Copper Tripeptide-1 (registered in EU Commission CosIng database) Gene expression modulation: 4 000 human genes (Connectivity Map dataset, Pickart 2015) Plasma level in healthy humans declines from ~200 ng/mL at age 20 to ~80 ng/mL at age 60 (62 % decrease) Most-studied bioactivities: fibroblast proliferation , type I/III collagen synthesis , antioxidant activity (SOD upregulation) Reference sources (PubMed) Pickart L., Vasquez-Soltero JM., Margolina A

Chronic insufficiencycan affect the spinal cord, peripheral nerves, optic nerve, and brain

Pepcid $25.00 Pepcid is a histamine-2 blocker that works by decreasing the amount of acid the stomach produces

Antioxidants 8:81 Gest N, Gautier H, Stevens R (2013) Ascorbate as seen through plant evolution: the rise of successful molecule

This "substituent effect" is general for dienes and trienes, and is even more pronounced for enone chromophores