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We recommend starting one compound first (typically the GLP-1 medication), stabilizing on that dose, and then adding the second compound

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Cell 87(3):391404 Chuang YY, Chen Y, Gadisetti Chandramouli VR, Cook JA, Coffin D, Tsai MH, DeGraff W, Yan H, Zhao S, Russo A, Liu ET, Mitchell JB (2002) Gene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells

Another current challenge in psychiatry is the validity of categorizing mental conditions into separate diseases