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Agarwal A, Gupta S, Sikka S

Landree LE, Hanlon AL, Strong DW, Rumbaugh G, Miller IM, Thupari JN, Connolly EC, Huganir RL, Richardson C, Witters LA, Kuhajda FP, Ronnett GV: C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism

These exacerbated inflammatory responses entail upregulation of the angiotensin-converting enzyme-2 (ACE2) receptor, to which the SARS-CoV-2 virus spike protein (S protein) binds, thereby gaining entry to host cells (11, 13)