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Treasury Index Fund Class I Utility Income Portfolio 2018-2 (Invesco Unit Trusts Utility Income Portfolio 2018-1 (Invesco Unit Trusts Utility Income Portfolio 2018-4 (Invesco Unit Trusts Ivy Asset Strategy Fund Class I Closed-End Strategy: Value Equity and Income Portfolio 2020-2 (Invesco Unit Trusts Ivy Value Fund Class N Ivy Global Bond Fund Class N Ivy Securian Core Bond Fund Class E Ivy Securian Core Bond Fund Class I Voya Small Company Portfolio Initial Ivy Energy Fund Class E Closed-End Strategy: Value Equity and Income Portfolio 2019-2 (Invesco Unit Trusts Ivy Energy Fund Class I Closed-End Strategy: Value Equity and Income Portfolio 2019-4 (Invesco Unit Trusts Ivy Government Money Market Fund Class E Federated International Strategic Value Dividend Fund A Federated International Strategic Value Dividend Fund C Federated International Strategic Value Dividend Fund IS Federated International Strategic Value Dividend Fund - R6 Shares VY Invesco Growth and Income Portfolio Adviser Investment Grade Corporate Trust Investment Grade Corporate Trust Investment Grade Corporate Trust Investment Grade Municipal Trust Intermediate Srs 41 Investment Grade Municipal Trust Invesco Unit Trust Investment Grade Income Tr 10-20 Year Srs 38 Investment Grade Income Tr 7+Year Srs 28 Investment Grade Municipal Tr Srs 162 Investment Grade Income Trust Investment Grade Income Trust 10-20 Year Srs 41 VY Invesco Growth and Income Portfolio Initial Investment Grade Municipal Tr Srs 159 Investment Grade Municipal Trust Investment Grade Municipal Trust Investment Grade Income Trust Investment Grade Income Trust Investment Grade Income Trust VY Invesco Growth and Income Portfolio Service Investment Grade Income Trust Investment Grade Municipal Trust VY Morgan Stanley Global Franchise Portfolio Service Ivy High Income Fund Class E Ivy High Income Fund Class I Ivy International Core Equity Fund Class A Ivy Global Growth Fund Class B IVA International Fund Class C Ivy International Core Equity Fund Class C Ivy Global Growth Fund Class A IVA International Fund Class A VY Invesco Equity and Income Portfolio S2 IVA International Fund Class I VY Invesco Growth and Income Portfolio S2 Ivy Global Growth Fund Class Y Ivy International Small Cap Fund Class A Ivy International Small Cap Fund Class C Ivy International Small Cap Fund Class I Ivy International Small Cap Fund Class N Ivy International Small Cap Fund Class Y VY Invesco Comstock Portfolio Adviser VY Invesco Comstock Portfolio Initial VY Invesco Comstock Portfolio Service Closed-End Strategy: Value Equity and Income Portfolio 2018-4 (Invesco Unit Trusts Ivy Limited-Term Bond Fund Class E Dividend Income & Value Portfolio 2019-1 (Invesco Unit Trusts Closed-End Strategy: Value Equity and Income Portfolio 2019-1 (Invesco Unit Trusts Investment Grade Income Trust 7+Year Srs 31 Investment Grade Municipal Trust Voya Money Market Portfolio Initial Ivy Global Growth Fund Class C Ivy Mid Cap Income Opportunities Fd Cl A Ivy Mid Cap Income Opportunities Fd Cl C Ivy Mid Cap Income Opportunities Fd Cl E Ivy Mid Cap Income Opportunities Fd Cl I Ivy Mid Cap Income Opportunities Fd Cl R Ivy Mid Cap Income Opportunities Fd Cl N Ivy Mid Cap Income Opportunities Fd Cl Y Closed-End Strategy: Value Equity and Income Portfolio 2020-1 (Invesco Unit Trusts Voya SmallCap Opportunities Portfolio Service Voya Small Company Portfolio Service Invesco Unit Tr Investment Grade Income Tr 10-20 Year Srs 37 VY Clarion Real Estate Portfolio Initial Digital Gaming Portfolio 2020-1 (Invesco Unit Trusts VY Clarion Real Estate Portfolio Service VY Clarion Real Estate Portfolio S2 Ivy Global Bond Fund Class A Ivy Global Bond Fund Class B Ivy Global Bond Fund Class C Investment Grade Municipal Trust Investment Grade Income Trust Ivy Global Bond Fund Class I Investment Grade Income Trust Voya SmallCap Opportunities Portfolio Initial Investment Grade Corporate Trust Investment Grade Municipal Trust Srs 168 Investment Grade Income Trust 7+ Year Srs 33 Investment Grade Corporate Trust Investment Grade Corporate Trust Ivy Global Bond Fund Class Y Ivy Managed International Opportunities Fund Class A Ivy Managed International Opportunities Fund Class B Investment Grade Corporate Trust Investment Grade Corporate Trust Ivy Managed International Opportunities Fund Class C Ivy Managed International Opportunities Fund Class E Investment Grade Income Tr 10-20 Year Srs 35 Ivy Managed International Opportunities Fund Class I Investment Grade Income Tr 20+Year Srs 40 Ivy Managed International Opp Class N Ivy Managed International Opportunities Fund Class Y Ivy Value Fund Class E Ivy Small Cap Core Fund Class I Ivy International Core Equity Fund Class Y IVA Worldwide Fund Class A IVA Worldwide Fund Class C IVA Worldwide Fund Class I The Dow Jones Total Market Portfolio Ivy Balanced Fund Class E Voya Diversified Emerging Markets Debt Fund Class W Voya Large Cap Value Fund Class W Ivy Wilshire Global Allocation Fund Class A Ivy Wilshire Global Allocation Fund Class B Ivy Wilshire Global Allocation Fund Class C Ivy Wilshire Global Allocation Fund Class E Ivy Wilshire Global Allocation Fund Class I Ivy Wilshire Global Allocation Fund Class N Ivy Wilshire Global Allocation Fund Class R Ivy Wilshire Global Allocation Fund Class Y Guinness Atkinson Global Innovators Fund - Investor Class The Dow Jones Select Dividend Index Strategy Portfolio 2019-1 (Invesco Unit Trusts Investors Quality Tax-Exempt Trust Series 181 Voya Global Perspectives Fund Class W Voya Russia Fund Class W Voya Short Term Bond Fund Class W Voya Global Equity Portfolio Class S2 Voya Index Solution 2035 Portfolio S2 Voya Index Solution 2025 Portfolio S2 Ivy Value Fund Class I Ivy Securian Core Bond Fund Class R Ivy Balanced Fund Class R Ivy Balanced Fund Class I Ivy Core Equity Fund Class R High Yield Corporate Trust Ivy Small Cap Core Class T Ivy Pzena International Value Fund Class R High Yield Corporate Trust Ivy Energy Fund Class R Ivy Global Equity Income Fund Class R Ivy Large Cap Growth Fund Class I Ivy Global Bond Fund Class R Ivy High Income Fund Class R Ivy Municipal High Income Fund Class A Ivy Municipal High Income Fund Class B Ivy Municipal High Income Fund Class C Ivy Global Growth Fund Class R Ivy Municipal High Income Fund Class N Ivy International Core Equity Fund Class R Ivy Municipal High Income Fund Class Y Ivy Limited-Term Bond Fund Class R Ivy Managed International Opportunities Fund Class R Ivy Mid Cap Growth Fund Class I Invesco Global Opportunities Fd Cl Y Ivy Emerging Markets Equity Fund Class R IVY APOLLO STRATEGIC INCOME FD CL Y Ivy Small Cap Core Fund Class A Ivy Small Cap Core Fund Class B Ivy Small Cap Core Fund Class C Ivy Small Cap Growth Fund Class I Ivy Small Cap Core Fund Class R Ivy Small Cap Growth Fund Class T Ivy Small Cap Core Fund Class Y Ivy Value Fund Class A Ivy Value Fund Class B Ivy Value Fund Class C Ivy Small Cap Core Fund Class E Ivy Value Fund Class R Ivy Value Fund Class Y Invesco Select Opportunities Fund Cl R6 Invesco International Companies Fund Cl A Invesco International Companies Fund Cl C Invesco International Companies Fund Cl R5 Invesco International Companies Fund Cl R Invesco International Companies Fund Cl R6 Invesco International Companies Fund Cl Y Invesco Select Opportunities Fd Cl A Invesco Select Opportunities Fd Cl C Invesco Select Opportunities Fd Cl R5 Invesco Select Opportunities Fd Cl R Invesco Select Opportunities Fd Cl Y Enhanced Sector Strategy John Hancock Fds II Alternative Asset Allocation Fund Class A JPMorgan SmartRetirement Blend 2060 Fund - R5 John Hancock Fd II Alternative Asset Allocation Fd Cl C Janus Henderson Enterprise Portfolio - Institutional Shares John Hancock Fds II James Alpha Multi-Strategy Alternative Income Fund Class A John Hancock Funds II Alternative Asset Allocation Fd Cl R2 John Hancock Funds II Alternative Asset Allocation Fd Cl R6 John Hancock Funds II Alternative Asset Allocation Fd Cl R4 JPMorgan SmartRetirement Blend 2060 Fund - R6 Janus Henderson Balanced Fund - T Shares Janus Henderson Balanced Fund - C Shares Janus Henderson Balanced Portfolio - Institutional Shares Janus Henderson Balanced Fund - N Shares Janus Henderson Balanced Fund - S Shares Janus Henderson Forty Portfolio - Institutional Shares Janus Henderson Forty Fund - C Shares James Alpha Multi-Strategy Alternative Income Fund Class C Janus Henderson Contrarian Fund - D Shares James Alpha Global Real Estate Ptf Class C JPMorgan SmartRetirement Blend 2060 Fund I Class Janus Henderson Forty Fund - T Shares Janus Henderson Flexible Bond Fund - S Shares Janus Henderson Growth and Income Fund - S Shares James Alpha Event Driven Portfolio Class A James Alpha Event Driven Portfolio Class C James Alpha Event Driven Portfolio Class I Janus Henderson Enterprise Fund - T Shares James Alpha Event Driven Portfolio Class S John Hancock Freedom 529 FUTURE Trends Portfolio Class A John Hancock Freedom 529 FUTURE Trends Portfolio Class C2 Janus Henderson Flexible Bond Fund - T Shares Janus Henderson Flexible Bond Portfolio - Institutional Shares Janus Henderson Adaptive Global Allocation Fund - A Shares Janus Henderson Global Technology and Innovation Fund C Shares Janus Henderson Adaptive Global Allocation Fund - D Shares JAGUAR GLOBAL PROPERTY FUND - INSTITUTIONAL SHARES Janus Henderson Growth and Income Fund - T Shares Janus Henderson Global Life Sciences Fund - T Shares Janus Henderson Adaptive Global Allocation Fund - N Shares Jaguar International Property Fund - Institutional Shares Janus Henderson Research Portfolio - Institutional Shares Janus Henderson Adaptive Global Allocation Fund - S Shares Janus Henderson Global Technology and Innovation Fund T Shares Janus Henderson Government Money Market Fund - T Shares James Alpha EHS Portfolio Class A James Alpha EHS Portfolio Class C James Alpha EHS Portfolio Class S Janus Henderson High-Yield Fund - T Shares Janus Henderson Overseas Portfolio - Institutional Shares James Alpha Multi-Strategy Alternative Income Fund Class I JPMorgan SmartRetirement 2060 Fund - A JPMorgan SmartRetirement 2060 Fund - C JPMorgan SmartRetirement 2060 Fund R5 Class JPMorgan SmartRetirement 2060 Fund - R3 JPMorgan SmartRetirement 2060 Fund - R4 JPMorgan SmartRetirement 2060 Fund I Class JPMorgan SmartRetirement 2060 Fund - R6 JPMorgan SmartRetirement 2060 Fund - R2 John Hancock Funds II Multimanager Lifestyle Aggressive Portfolio Class A John Hancock Funds II Multimanager Lifestyle Balanced Portfolio Class A John Hancock Funds II Multimanager Lifestyle Growth Portfolio Class A John Hancock Funds II Multimanager Lifestyle Moderate Portfolio Class A JPMorgan Systematic Alpha Fund - R6 John Hancock Funds II Multimanager Lifestyle Conservative Portfolio Class A American Mutual Portfolio A JP Morgan Mid Cap Value Fund-A Share Class Jamestown Equity Fund (The) - Williamsburg Investment Jacob Internet Fund Investor Class Shares American Mutual Portfolio C2 Janus Henderson Research Fund - T Shares Janus Henderson Mid Cap Value Portfolio - Institutional Shares Janus Henderson Money Market Fund - T Shares Janus Henderson Balanced Fund - D Shares Janus Henderson Enterprise Fund - D Shares Janus Henderson Flexible Bond Fund - D Shares Janus Henderson Triton Fund - D Shares Janus Henderson Global Select Fund - D Shares Janus Henderson Venture Fund - D Shares Janus Henderson Global Research Fund - D Shares Janus Henderson Overseas Fund - T Shares Janus Henderson Large Cap Value Fund - A Shares Janus Henderson Large Cap Value Fund - C Shares Janus Henderson Large Cap Value Fund - I Shares Janus Henderson Large Cap Value Fund - S Shares Janus Henderson Asia Equity Fund - A Shares Janus Henderson Asia Equity Fund - C Shares Janus Henderson Asia Equity Fund - D Shares Janus Henderson Asia Equity Fund - I Shares Janus Henderson Asia Equity Fund Class N Shares Janus Henderson Asia Equity Fund - S Shares Janus Henderson Asia Equity Fund - T Shares James Alpha Global Real Estate Investments Portfolio Class A James Alpha Global Real Estate Investments Ptf Class I James Alpha Global Real Estate Investment Portfolio Class S Janus Henderson Forty Fund - S Shares Janus Henderson Short-Term Bond Fund - T Shares James Small Cap Fund Class A (The) James Alpha Multi-Strategy Alternative Income Portfolio Class S John Hancock Funds II New Opportunities Fund Class A James Alpha Structured Credit Value Portfolio Class S James Alpha Structured Credit Value Portfolio Class A Janus Henderson Global Technology and Innovation Fund A Shares Janus Henderson Global Technology and Innovation Fund I Shares Janus Henderson Global Technology and Innovation Fund N Shares JPMorgan SmartRetirement Blend 2060 Fund - R2 JPMorgan SmartRetirement Blend 2060 Fund - R3 Janus Henderson Global Technology and Innovation Fund S Shares Janus Henderson Triton Fund - T Shares JPMorgan SmartRetirement Blend 2060 Fund - R4 James Aggressive Allocation Fund Janus Henderson Adaptive Global Allocation Fund - C Shares Janus Henderson Venture Fund - T Shares Janus Henderson Global Research Portfolio - Institutional Shares Janus Henderson Global Research Fund - T Shares John Hancock Fds John Hancock Fds Janus Henderson Balanced Fund - I Shares John Hancock Fds John Hancock Balanced Fd Cl R2 John Hancock Fds John Hancock Balanced Fd Cl R6 JPMorgan SmartRetirement Blend 2025 Fd R5 Blue Chip Growth Portfolio A Blue Chip Growth Portfolio C2 John Hancock Bond Fund Class R4 John Hancock Funds II Blue Chip Growth Fund Class A John Hancock Funds II Blue Chip Growth Fund Class C Aberdeen Total Return Bond Fund Class I John Hancock Funds II Multimanager Lifestyle Aggressive Portfolio Class B John Hancock Funds II Multimanager Lifestyle Balanced Portfolio Class B John Hancock Funds II Multimanager Lifestyle Conservative Portfolio Class B John Hancock Funds II Multimanager Lifestyle Growth Portfolio Class B John Hancock Funds II Multimanager Lifestyle Moderate Portfolio Class B John Hancock ESG Core Bond Fund Class A John Hancock ESG Core Bond Fund Class I John Hancock ESG Core Bond Fund Class R6 JPMorgan SmartRetirement Blend 2025 Fd R2 John Hancock Funds II New Opportunities Fund Class C JPMorgan SmartRetirement Blend 2020 Fd R5 JPMorgan SmartRetirement Blend 2025 Fund I Class JPMorgan SmartRetirement Blend 2025 Fund - R4 JPMorgan SmartRetirement Blend 2025 Fund - R3 JPMorgan SmartRetirement Blend 2025 Fd R6 Janus Henderson Global Allocation Fund - Conservative - A Shares Janus Henderson Global Allocation Fund - Conservative - C Shares John Hancock California Tax-Free Income Fund Class I Janus Henderson Global Allocation Fund - Conservative - I Shares Janus Henderson Forty Fund - I Shares Janus Henderson Global Allocation Fund - Conservative - S Shares JPMorgan California Tax Free Bond A JPMorgan California Tax Free Bond Fund Class C JPMorgan Core Plus Bond Fund Class L JPMorgan Core Bond Fund-R3 JPMorgan Core Bond Fund-R4 JPMorgan Core Bond R5 JPMorgan California Tax Free Bond Fund Class R6 JPMorgan Core Bond Fund R6 JPMorgan Core Bond Fund R2 John Hancock Small Cap Core Fund Class A John Hancock Small Cap Core Fund Cl I ALPS / CoreCommodity Management CompleteCommodities Strategy Fund - Class A JPMorgan California Municipal Money Market Fund E Trade John Hancock Funds II Multi-Index 2060 Preservation Portfolio Class 1 JPMorgan Intrepid Growth Fund Class C JPMorgan Core Focus SMA Fund John Hancock Funds II Multimanager Lifestyle Aggressive Portfolio Class C John Hancock Funds II Multimanager Lifestyle Balanced Portfolio Class C John Hancock Funds II Multimanager Lifestyle Conservative Portfolio Class C John Hancock Funds II Multimanager Lifestyle Growth Portfolio Class C John Hancock Funds II Multimanager Lifestyle Moderate Portfolio Class C JPMorgan Mid Cap Equity Fund Cl A JPMorgan Municipal SMA Fund JP Morgan Mid Cap Value Fund-C Share Class Janus Henderson Contrarian Fund - A Shares Janus Henderson Contrarian Fund - C Shares Janus Henderson Contrarian Fund - S Shares Janus Henderson Contrarian Fund N shares Janus Henderson Contrarian Fund - R Shares JPMorgan New York Tax Free Bond C Janus Henderson Contrarian Fund - I Shares JPMorgan Core Plus Bond Fund-R3 JPMorgan Core Plus Bond Fund-R4 JPMorgan U.S

Calibration: always use calibrated pipettes or syringes

Protocol comparison table Complete reconstitution guide Proper reconstitution is as important as dosing