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In vitro models demonstrated that GSTM1 markedly attenuated collagen secretion and activation of fibroblasts, as well as suppressed their proliferation and migration

Additionally, inhibiting Ang II has a positive impact on endothelial function in patients with hypertension and MetS [173], and patients with hypertension-associated ED can benefit from the treatment with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers [174]

According to some clinic studies about this, it significantly showed an increased risk of having thyroid tumors in animal subjects

[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Zeng Y., Adamson R.H., Curry F.R.E., Tarbell J.M

Therefore, further replications are needed