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The optimal administration route in humans has not been definitively established through clinical trials

Ness-Abramof R, Nabriski DA, Braverman LE, Shilo L, Weiss E, Reshef T, Shapiro MS, Shenkman L

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This improved blood circulation means more production of brain-derived neurotrophic factor (BDNF), which leads to an improvement in memory and thinking two things that are key to mental wellness