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doi: 10.1038/s41422-022-00642-w 2 ChenHQiQWuNWangYFengQJinRet al

Genome-wide association of serum bilirubin levels in Korean population

Evidence shows that isolated leucine supplementation becomes ineffective, and may even have unfavorable consequences, when other essential amino acids are limited or when systemic amino-acid dysregulation is present

this leaves the infected individual susceptible to opportunistic infections, including Pneumocystis pneumonia (PCP), tuberculosis, herpes simplex virus, and Kaposi's sarcoma