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Patients with pernicious anaemia may therefore experience joint symptoms related to concurrent autoimmune conditions rather than the B12 deficiency itself

It sounds like you also have other health issues to cope with, but PA seems a possible, especially given family history

Since this vitamin regulates melanin production, a deficiency can contribute to unwanted pigmentation issues

Its a common, although often overlooked, symptom of endometriosis

Furthermore, TSEL nanovesicles co-delivering BACE1 siRNA and a TREM2 plasmid effectively penetrated the BBB and accumulated at AD lesions in vivo in APP/PS1 mice (Jiang et al., 2024)