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2017-T1/BMD-5468 2018-2020.- IP: Alvaro Gutierrez Uzquiza

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This process effectively transforms radiotherapy into an in situ vaccination strategy that induces ICD and potentiates ICIs responses [292, 293]

proposed that a the phospholipid/Ca++ dependent brain pkc participated in the expression of neuroplasticity and demonstrated this effect using the phorbol acetate TPA to enhance the action of pkc to maintain LTP in rat hipoccampal neurons (Routtenberg et al., 1986), in effect, producing a a long-lasting potentiation of synaptic activation (Nogus, 1997)