Haemodialysis was initiated to decrease the high serum VPA concentration and L-carnitine therapy (50 mg/kg per day for 4 days) was empirically started
miRNA data were analyzed in R through DESeq2, with significance accepted with FDR 0.1
If the ability to reduce GSSG to GSH is overwhelmed by a high burden of oxidative stress, GSSG can be exported out of cells or react with protein sulphydryl groups to prevent a major shift in the redox equilibrium [11], thereby depleting cellular GSH
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