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Importantly, berberine should not replace evidence-based medications like statins but rather be integrated alongside lifestyle modifications and guideline-directed therapies

2018 Feb;16(2):e05172

doi: 10.3390/cancers14194715 201 McMahonAChenWLiF

4-HNE and MDA not only act as the main biomarkers for lipid peroxidation assessment and contribute to multiple pathological processes during OA development

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