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In obese microenvironments, ATF4 acts as a metabolic stress sensor, transcriptionally upregulating protein disulfide isomerase a3 (PDIA3) to drive TNF-, IL-6 and chemokine (C-C motif) ligand 2 (CCL2) production, thereby intensifying adipose tissue inflammation (177)

Based on the class Arachnida arthropod animal medicinal value and antibacterial activity investigation

Neutrophil extracellular traps persist at high levels in the lower respiratory tract of critically ill COVID-19 patients

ABSTRACT HIV infects and destroys CD4+ T cells leading to compromised immune system

Elevated production of ROS in C9orf72-associated ALS is also associated with abnormalities in mitochondrial function and neuroinflammation (Briehl et al., 80 DPRs interact with Atp5a1, which compromises mitochondrial functions in mice due to increased ROS production (Choi et al., 2019)