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Maximum recommended doses: - In children weighing less than 40 kg, the total dose of paracetamol should not exceed 80 mg/kg/d (see Overdosage section) For information, - in children between 41 kg and 50 kg, the total dose of paracetamol should not exceed 3 g/day (see Overdosage section), - in adults and children weighing over 50 kg, THE TOTAL DOSE OF PARACETAMOL SHOULD NOT EXCEED 4 GRAMS PER DAY (see Overdose section)

Neuroprotective properties may help damaged nerve fibers recover function

Figure 2 - Comparison of mean SEM AST

Drugs with short elimination half-lives do not accumulate significantly so there is relatively little delay before the drug reaches therapeutic concentrations and a loading dose is unnecessary

J Cell Biochem 2001