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Safety Considerations and When Provider Guidance Is Essential Glutathione is generally well-tolerated, but excessive supplementation may cause gastrointestinal upset, headaches, or rarely allergic reactions

& Holick, M

Mangels groer Humanstudien lsst sich keine abschlieende Sicherheitsbewertung treffen

doi: 10.18596/jotcsa.913136 [DOI] [Google Scholar] 33

Receptor activation promotes regulatory T-cell (Treg) differentiation and activity, increases the production of anti-inflammatory cytokines such as interleukin-18 (IL-18), and helps maintain the Th17/Treg balance, thereby attenuating the pro-inflammatory responses characteristic of active IBD [17, 18]