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In the assessment of the effect of salicin on arthritis in vivo, treatment with 15 mg/kg salicin resulted in a reduction in clinical arthritis scores, accompanied by a significant improvement in histopathology (joint stenosis, cartilage destruction, synovial hyperplasia and inflammatory cell infiltration) in rats

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Western blots were visualized using ECL substrate (Yeasen, China), and protein bands were quantified using Gel-Pro-Analysis software

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Common locations include the upper arm, abdomen, back, or thigh