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Yes, you can have acanthosis nigricans on your face, including your nose, mouth, and eyelids, but this is rare.

These side effects generally go away after you take the medicine for a while

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doi: 10.1038/nature03314 84 LiuYDentinRChenDHedrickSRavnskjaerKSchenkSet al

Melanoma cells arising from the immature melanocytes that have become arrested in the lamina propria of the oral mucosa proliferate, forming nodular aggregates in the lamina propria/submucosa with or without breaching the subepithelial basement membrane