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Lactobacillus rhamnosus GG culture supernatant ameliorates acute alcohol-induced intestinal permeability and liver injury

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10.1034/j.1600-0463.2002.100604.x APMIS

ATPase activity assays confirmed that coumarin stimulates ATP hydrolysis by P-glycoprotein (P-gp), indicating that coumarin acts as a substrate for it, and the nanoparticles were shown to inhibit P-gp-mediated efflux, enhancing drug retention in cells