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The following exclusion criteria were applied: a history or presence of cholelithiasis, diabetes, tumours in the pituitary gland or hypothalamus, any serious allergy, positive serological test for hepatitis B or C and HIV, hypertension or other significant cardiovascular abnormality

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Lipotropic compounds improve fat oxidation, but without a muscle preservation stimulus, you'll lose lean mass alongside fat, which lowers metabolic rate and makes long-term maintenance harder

Peak appetite suppression in the first 48 hours after injection can make eating enough during feeding windows genuinely difficult