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A complex cytokine influence at the maternal-fetal interface creates the conditions that are necessary to support embryo implantation in the endometrium [92, 93]

9 Longer duration of antidepressant use greatly increases the likelihood, severity, and potential duration of withdrawal effects

Pneumonia caused by drug-resistant bacteria is harder to treat and may lead to longer illness and greater risk of death (Bosso 2011)

It is important to note that, despite these convergent findings, direct mechanistic evidence demonstrating that addictive substances induce depressive phenotypes via specific epigenetic pathways remains extremely limited, with only a few studies providing clear causal links