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micropetrosis and the canalicular system disruption cause this, leading to bone fragility

Treat 145 YuY.HuangJ.ChenX.FuJ.WangX.PuL.et al (2022)

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doi: 10.1016/j.scitotenv.2013.03.083 198 ZakyA

To determine whether induced expression of IRF5 and IKK effectively reprogrammed macrophages from M2 to M1, researchers generated M2 macrophages by culturing bone marrow-derived macrophages (BMDMs) with IL-4