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ALX-0171 a trivalent nanobody targeting the fusion protein of respiratory syncytial virus achieves efficient deposition in the lower respiratory tract, potently neutralizing respiratory syncytial virus at early stages of infection and reducing viral replication in preclinical models 238,239

Gastric and lingualas well as pharyngeallipases belong to a family of serine hydrolases that have acidic pH optima (pH 4), are stable in the acidic environment of the stomach, are resistant to digestion by pepsin, and are not inhibited by the surface layer of membrane lipids (emulsifiers) that envelopes TAG droplets

and Chaumont, F., Aquaporin-facilitated transmembrane diffusion of hydrogen peroxide, Biochim