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149 A cross-sectional study in adolescent girls noted a relationship between morning circadian misalignment, based on irregular melatonin secretion, and PCOS-related metabolic disturbance

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Targeted Metabolomics of CSF in Healthy Individuals and Patients With Secondary Progressive Multiple Sclerosis Using High-Resolution Mass Spectrometry

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Conversely, a separate six-month randomized controlled trial revealed that a curcumin-galactomannan complex (400 mg twice daily) significantly improved Mini-Mental State Examination (MMSE) and Geriatric Locomotive Function Scale (GLFS) scores of AD patients compared to both placebo and unformulated standard curcumin, suggesting a potential delay in disease progression ( 4.2 Parkinsons disease 4.2.1 Pathogenesis of PD Parkinsons disease (PD) is the second most prevalent neurodegenerative disorder after AD, mainly manifested as motor dysfunction and cognitive decline