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Thus, creatine synthesis and Hcy formation are metabolically connected ( Reference Taes, Delanghe and De Vriese 6 ) (Fig

Furthermore, the molecular mechanism underlying RRM2 s tumor-promoting function was preliminarily investigated through mRNA sequencing and subsequent experiments

Additionally, the availability of samples from age-matched UFMs provided a cross-reference of the healthy state, even though BMI was not considered for the comparisons

The metabolic alterations associated with abdominal fat accumulation in obese patients, such as hypertriglyceridemia and declined levels of HDL-C, have been well documented (186)