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however, clinical treatment still faces numerous challenges: 30%-40% of patients exhibit primary or secondary non-response to existing therapeutic regimens such as biologics and small-molecule drugs, and prolonged administration tends to induce significant side effects

C., Lin, M

Essential reactions for the host and viral metabolism The Flux Balance Analysis (FBA) method (Orth et al, 2010) was used to compute both the biomass maintenance of the cell in the absence of virus and the maximum growth rate of the virus in the cell (host optimum and virus optimum conditions)

Physiol Plant 143(1):19

BMJ Open Respiratory Research