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271 : 796800 Butler LM, Zhou X, Xu WS, Scher HI, Rifkind RA, Marks PA and Richon VM (2002) The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin

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This approach allowed us to measure the fluorescence lifetime of NAD(P)H and distinguish between its free and enzyme-bound forms, providing quantitative information on cellular metabolic state