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In this study, we demonstrated that Np63 regulates GSH, which scavenges ROS and is generated from serine and glycine, in a NRF2-dependent manner

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Ag + and Cu 2+ favor an M2-like reparative phenotype over pro-inflammatory M1 macrophages, while Zn 2+ enhances neutrophil and macrophage function and suppresses excessive cytokine production 210,211,212