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2008 Dec;88(6):1511-8

To quantity the GSH metabolism status and stratify THCA patients, we further constructed a 9-gene based signature via LASSO-penalized Cox regression model

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It selectively targets monocytes and tumor-associated macrophages, downregulating the production of inflammatory mediators in the tumor microenvironment, along with conventional direct cytotoxic effects [12,13,14,15,16]