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Three decades of nucleic acid aptamer technologies: lessons learned, progress and opportunities on aptamer development

10 These therapies often fail due to tumor resistance, significant side effects, and limitations such as high cost and patient inconvenience

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The hydroxylation of proline and lysine is carried out by the enzyme prolyl hydroxylase using ascorbic acid as co-factor

This fact is causing some excitement in the hope that GSH may have a role in management and cessation of neurodegenerative processes involved in these conditions