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This observation supports evidence from other studies, such as the work of Histopathologically, while GABA supplementation helped in preserving some aspects of hippocampal structure, significant neurodegeneration and reduced neuron density remained, particularly in the CA4 region, similar to what was observed in the PPA-treated group

Mohan RA, Boukens BJ, Christoffels VM

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It was evident that decreased levels of oxidative stress in the brain were associated with treatment [74]

In contrast, other studies reported that smoking reduces serum uric acid levels and has a protective effect against the risk of gout 7-10