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The methionine input (in our model) is 40 M/hr, and if the mass leaving via the polyamine pathway (AMD1) is subtracted, the CBS flux is obtained because at steady state, the mass has nowhere else to go

This analysis is based on the principle that the presence of triiodide in a solution can be confirmed by the addition of amylose, at which point the solution will turn a dark purple

Clin Exp Pharmacol Physiol 34:906911

PD studies have shown a decline in kynurenic acid levels with elevation in 3-hydroxykynurenine levels favoring neurotoxic states in the frontal cortex, putamen and substantia nigra pars compacta brain regions (75, 77)