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Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R

Notably, we observed increased fibrosis in Aldh1l2 KO mice at day 4 following caerulein treatment and a delay in the regeneration of acinar cells at day 7, consistent with a role for re-expression of ALDH1L2 in the recovery from pancreatic damage (Extended Data Fig

Macrophage-derived IL-6 for example upregulates lipolysis in adipocytes leading to an increased flux of fatty acids and glycerol into the liver (12)

The different site of CD isoforms with a different specificity for the reduced and oxidized substrate forms implies that reduced glutathione and Cys-Gly must spread through the apoplastic space before they are cleaved by the corresponding enzyme