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Therefore, targeted intervention at critical junctions along the E-P-OS network may resolve this clinical challenge

chrysophanol primarily activates the Keap1/Nrf2/HO-1 pathway to augment intracellular antioxidant capacity, diminish reactive oxygen species generation, and suppress TGF-1 and -SMA expression

When the vagus nerve is compromised, it leads to severe autonomic nervous system dysfunction (dysautonomia), explaining the rapid heart rates, digestive issues, and profound cognitive impairment that define the chronic Lyme experience

Antioxidant potential in esophageal, stomach and colorectal cancers

Am J Physiol 318(6):14741486