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The acyl-CoA synthetase short-chain family members (ACSSs) can convert short-chain fatty acids into short-chain acyl-CoA, and the acetic acid, transported into tumor cells, is mainly catalyzed by nuclear-cytoplasmic localized ACSS2, rather than mitochondrial-localized ACSS1, ACSS3, to produce acetyl-CoA [48]

The resulting carbanion attacks the carbonyl carbon of the donor ketose substrate

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Understanding the difference between research and pharmaceutical grade peptides adds context to why testing matters