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Description

Linkermann, A., Stockwell, B

In clinical studies, the results have been conflicting

Lactate dehydrogenase A-coupled NAD(+) regeneration is critical for acute myeloid leukemia cell survival

Hughson AL, Hannon G, Salama NA, Vrooman TG, Stockwell CA, Mills BN, Garrett-Larsen J, Qiu H, Katerji R, Benoodt L, Johnston CJ, Murphy JD, Kruger E, Ye J, Gavras NW, Keeley DC, Qin SS, Lesch ML, Muhitch JB, Love TMT, Calvi LM, Lord EM, Luheshi N, Elyes J, Linehan DC, Gerber SA Molecular therapy