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It exists as a soluble, 23 kDa protein located in the cytoplasm due to a strong nuclear export signal 25 , although some reports suggest that the protein may shuttle between the cytosol and the nucleus 26,27,28

Polyps harbor increased numbers of activated mast cells, which release substantial ROS and inflammatory mediators

The consistency of enzyme level normalization with histological findings strengthens the reliability of the results

This medication should be used with caution in individuals with a history of allergies, as rare allergic reactions have been reported

The system enables one-step purification, tag cleavage, and elution, yielding tag-free proteins with over 98% purity