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Mice with increased hepcidin expression showed an increase in total hemoglobin levels and a corresponding increase in red blood cell lifespan, suggesting that hepcidin agonists may help treat abnormal iron absorption in patients with -thalassemia and related diseases

Low level of heterogeneity ( I 2 =0%) and inconsistency (Cochrans Q =0.01, P =0.93) was confirmed

On the other hand, the excessive activation of Nrf2/HO-1 disrupts the balance of iron ion metabolism, leading to ferroptosis [288, 289]

However, phytomelatonin levels depend on ripeness stage and postharvest conservation and, in addition, abiotic stressors modulate its production

The role of acetaldehyde outside ethanol metabolism in the carcinogenicity of alcoholic beverages: Evidence from a large chemical survey