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doi: 10.1152/ajpendo.00306.2020 56 PalMFebbraioMAWhithamM

This pressure can wear away the nerves protective covering (myelin), making it overly sensitive

MSCs release cytokines that improve insulin response in muscles, the liver, and fat, thereby stabilizing blood sugar

These genetic alterations are likely to interplay with epigenetic aspects of DNA methylation and histone modifications (a phenomenon referred to as epistasis), along with environmental interventions, leading to the overall individual susceptibility to GD