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Understanding the pharmacokinetic behaviour of HTY is essential for interpreting its biological effects and translational relevance

The liver mass and triglyceride content were significantly reduced, and citrate synthase activity was increased after NMN treatment in HFD-fed mice, which suggested that NMN could increase catabolism of fats

61 , PL 243-PL 248

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Excessive methylglyoxal is detoxified in part by glyoxalase I, which converts methylglyoxal into S-D-lactoylglutathione in the presence of glutathione (Inoue and Kimura, 1996)