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In one study, 21% of those with peripheral artery disease showed signs of venous insufficiency on vascular imaging, and the presence of venous insufficiency was correlated with increased severity of arterial disease

A study published in The New England Journal of Medicine showed that male participants over 60 years old, who took hGH for six months gained on average 8.8% lean body mass and lost 14% fat mass

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However, three real risks exist: reduced therapeutic effect (dangerous for diabetes management), potential contamination in older opened vials, and possible immunogenic responses from aggregated peptides

Clinical data shows palpitations occur in approximately 5-8% of GLP-1 users, often during dose escalation or in individuals with underlying cardiac sensitivity