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Use of this phrase has caused confusion, and its use should be avoided

Research should be limited to in vitro studies and approved preclinical laboratory models

Unless explicitly stated the mice were sacrificed 16 h after the CS exposure via cardiac exanguastion and bronchoalveolar lavage (BAL) was performed using two 750 L rinses of cold isotonic potassium phosphate solution

Initially, scientists have concentrated on EDCs acting via the so-called EATS (estrogen, androgen, thyroid, and steroidogenesis) pathways and, more recently, attention has been drawn to chemicals that exert effects also through non-EATS modalities [23]

Zhukauskas R, Fischer DN, Deister C, Alsmadi NZ, Mercer D